Keystone Symposia 2018 Workshop

WASHU EPIGENOME BROWSER

2018 Keystone Symposia, DNA and RNA Methylation (A7)

Description

Advances in next-generation sequencing platforms have reshaped the landscape of genomic and epigenomic research as well as human genetics studies. Annotating the non-coding, regulatory genome with genomic and epigenomic data has provided new venues to interpret the functional consequences of genetic variants associated with human complex traits. Large consortiums such as ENCODE and Roadmap Epigenomics project have generated tens of thousands of sequencing-based genome-wide datasets, creating a reference and resource for the scientific community. There is a great need for investigators to effectively engage with this resource in the context of analyzing investigators’ own data.

This interactive workshop will introduce The WashU Human Epigenome Browser and associated tools (http://epigenomegateway.wustl.edu/). The Epigenome Browser hosts ENCODE data and Human Epigenome Atlas data produced by the Roadmap Epigenomics project, and supports navigation of the data and its interactive visualization, integration, comparison, and analysis. Attendees will gain hands-on experience with exploring the most current epigenomic resources, and with advanced visual-bioinformatics tools including gene set view, genome juxtaposition, and chromatin-interaction display, inventions unique to the WashU Epigenome Browser. Through specific examples, the workshop will demonstrate the power of the Epigenome Browser.

Presenters

Ting Wang

Renee Sears

Josh Jang

When and Where

14:30—16:30 TUESDAY, JANUARY 23
British/Columbia Ballroom, Fairmont Hotel Vancouver, Vancouver, British Columbia, Canada

Browser Booklet

• Download a PDF version.

Tutorial Book

• Download a PDF version.

Agenda

1. Ting Wang : Engaging today’s epigenomic resources: An overview of past projects and future directions.
2. Renee Sears: The WashU Epigenome Browser’s basic functionality and a bivalent chromatin example.
3. Josh Jang: Viewing long range interactions with the WashU Epigenome Browser.

Heart Gene Set

Long Range Chromatin Interaction Workshop Sessions:

Part 1: http://epigenomegateway.wustl.edu/browser/?genome=hg19&datahub=http://wangftp.wustl.edu/~jjang/workshop/Part1

Part 2: http://epigenomegateway.wustl.edu/browser/?genome=hg19&datahub=http://wangftp.wustl.edu/~jjang/workshop/Part2