Advances in next-generation sequencing platforms have reshaped the landscape of genomic and epigenomic research as well as human genetics studies. Annotating the non-coding, regulatory genome with genomic and epigenomic data has provided new venues to interpret the functional consequences of genetic variants associated with human complex traits. Large consortiums such as ENCODE and Roadmap Epigenomics project have generated tens of thousands of sequencing-based genome-wide datasets, creating a reference and resource for the scientific community. There is a great need for investigators to effectively engage with this resource in the context of analyzing investigators’ own data.
This interactive workshop will introduce The WashU Human Epigenome Browser and associated tools (http://epigenomegateway.wustl.edu/). The Epigenome Browser hosts ENCODE data and Human Epigenome Atlas data produced by the Roadmap Epigenomics project, and supports navigation of the data and its interactive visualization, integration, comparison, and analysis. Attendees will gain hands-on experience with exploring the most current epigenomic resources, and with advanced visual-bioinformatics tools including gene set view, genome juxtaposition, and chromatin-interaction display, inventions unique to the WashU Epigenome Browser. Through specific examples, the workshop will demonstrate the power of the Epigenome Browser.
15:30-16:30 MONDAY, MARCH 21
Whistler Conference Centre, Whistler, British Columbia, Canada
List of session links:
chr1 10353111 10353112 chr1 85772008 85772009 chr1 93303602 93303603 chr1 101331535 101331536 chr1 101407518 101407519 chr1 117038286 117038287 chr1 117100956 117100957 chr1 117104214 117104215 chr1 179469313 179469314 chr10 6099044 6099045 chr10 6102011 6102012 chr10 6110828 6110829 chr10 43814048 43814049 chr10 81036006 81036007
Workshop at 2015 Keystone: Epigenomic Annotation of Transposable Elements Using The Washington University Epigenome Browser.
Workshop at 2014 ASHG: Epigenomic Annotation of Genetic Variants Using The Washington University Epigenome Browser.