Roadmap Epigenomic Tutorial 2015

Workshop at 2015 Keystone Symposia: Keystone joint meeting on Epigenomics and DNA methylation


Advances in next-generation sequencing technology have reshaped the landscape of genomic and epigenomic research as well as human genetics studies. Annotating the non-coding, regulatory genome with genomic and epigenomic data has provided new venues to interpret the functional consequences of genetic variants associated with human complex traits. Large consortiums such as ENCODE and Roadmap Epigenomics project have generated tens of thousands sequencing-based genome-wide datasets, creating a reference and resource for the scientific community. There is a great need for investigators to effectively engage with this resource in the context of analyzing investigators’ own data.

This interactive workshop will introduce The WashU Human Epigenome Browser and associated tools ( The Epigenome Browser hosts ENCODE data and Human Epigenome Atlas data produced by the Roadmap Epigenomics project, and support navigation of the data and its interactive visualization, integration, comparison, and analysis. Attendees will gain hands-on experience with exploring the most current epigenomic resources, and with advanced visual-bioinformatics tools including gene set view, genome juxtaposition, and chromatin-interaction display, inventions unique to the WashU Epigenome Browser. Through specific examples the workshop will demonstrate the power of annotating genetic variants with epigenomic data, and how it can be easily achieved with the Epigenome Browser.


Vasavi Sundaram

Wouter Meuleman

Manolis Kellis

Ting Wang

When and Where

14:30—16:30 MONDAY, MARCH 30
Longs/Grays Peaks, Keystone Resort, Keystone, Colorado, USA


  1. Ting Wang: Engaging today’s epigenomic resources
  2. Manolis Kellis: The NIH Roadmap Epigenomics Project
  3. Wouter Meuleman:
    • Part 1: Overview of the supplementary website of the Roadmap Epigenomics project, download pdf
    • Part 2: Analysis and visualization of hundreds of epigenomes, download pdf
  4. Vasavi Sundaram: Tutorial of the WashU Epigenome Browser
  5. Ting Wang: Epigenomic annotation of genetic variants using the Roadmap Epigenome Browser

Past Workshop

American Society of Human Genetics 2014

Workshop at 2014 ASHG: Epigenomic Annotation of Genetic Variants Using The Washington University Epigenome Browser.